Publications by authors named "M A Randazzo"

Autism Spectrum Disorder (ASD) is a complex condition with a multifactorial aetiology including both genetic and epigenetic factors. MicroRNAs (miRNAs) play a role in ASD and may influence metabolic pathways. Glycosylation (the glycoconjugate synthesis pathway) is a necessary process for the optimal development of the central nervous system (CNS).

View Article and Find Full Text PDF
Article Synopsis
  • Chest pain can often be misdiagnosed and has many potential causes, some of which are serious and require quick diagnosis.
  • The text describes a rare case where a patient had a combination of severe conditions: a heart attack, aortic dissection, pulmonary embolism, and pneumothorax.
  • A team of healthcare professionals worked together effectively to manage and treat this complex situation.
View Article and Find Full Text PDF

Introduction: Most patients suffering from neurological disorders endure varying degrees of upper limb dysfunction, limiting their everyday activities, with only a limited number regaining full arm use. Robotic and technological rehabilitation has been demonstrated to be a feasible solution to guarantee an effective rehabilitation to recover upper limb performance or to prevent complications of upper limb immobility. However, there is currently a lack of studies which analyze the sustainability of robotic and technological rehabilitation by comparing its costs to conventional rehabilitation pathways.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates the recovery of cardiac diagnostic procedures in Italy one year after the COVID-19 outbreak, focusing on procedure volumes, practices, and staff well-being.
  • A global survey revealed a 72% drop in cardiac diagnostic procedures in April 2020 compared to March 2019, with only a slight recovery (3% increase) by April 2021, though some specific tests showed increased volumes.
  • Many healthcare centers adopted measures like physical distancing and COVID-19 screening, but 25% of physicians reported high psychological stress levels, highlighting ongoing challenges within the healthcare system.
View Article and Find Full Text PDF
Article Synopsis
  • The study examines how aortic pulsatility index (API) and cardiac power output (CPO) can help assess heart function in patients with cardiogenic shock (CS) after administering a milrinone bolus.
  • In a group of 224 patients with severe CS, those with lower baseline API and CPO had a higher risk of needing advanced heart treatments or dying within a year.
  • The findings suggest that using API and CPO measurements can effectively stratify risk and predict outcomes in these patients, enhancing clinical decision-making.
View Article and Find Full Text PDF