Med Parazitol (Mosk)
October 2002
In November 2000, an outbreak of Giardiasis intestinalis with aqueous transmission was recorded in one of the microdistricts of Perm. Thirty six children aged 1-7 years fell ill, 2 parasitic carriers were identified among the staff. The diagnosis was parasitologically verified in all children with clinical manifestations.
View Article and Find Full Text PDFSeveral novel phosphatidic acid derivatives of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine were synthesized, which contained dialkylphosphatidyl, dialkylthiophosphatidyl moieties, as well as diacylphosphatidyl moiety with either 14,14,14-trifluoro-12-oxatetradecanoyl or natural acyl residues inherent in egg yolk phosphatidylcholine. Diacylphosphatidyl derivatives of glycyrrhetinic acid were also prepared. All the synthesized compounds exhibited significant anti-HIV activity.
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