[Neoadjuvant therapy of breast cancer using Newcastle disease virus].

The role of Newcastle disease virus and neoadjuvant therapy was assessed in 84 cases of breast cancer T1-4N0-2M0 (2005-2008). Combined use of the virus vaccine and chemotherapy (group A), therapy with the vaccine alone (group B) and chemotherapy regimen identical with that used in group A (group C) were compared. Histological pattern of tumor and stage were identified using expression of receptors of steroid hormones, oncoproteins Her2/neu and p53 as well as proliferation activity (marker Ki-67) before and after therapy.

[Myofixation in the patho- and sanogenesis of lumbar osteochondrosis].

Neuroorthopedic , electromyographic and neuropsychological examinations of patients with lumbar osteochondrosis have shown that dynamic myofixation in health is regulated by the preceding muscular reactions. When these mechanisms are impaired, the disease is characterized by an early onset and a severe course. With the development of osteochondrosis the myofixation in the damaged spinal segment is regulated by the reflex responses to the impulses from the zone of the damaged disk and from the focus of aseptic inflammation developing there rather than by the preceding muscular reactions.