Elucidation of retention mechanism of dipeptides on a ristocetin A-based chiral stationary phase using a combination of chromatographic and molecular simulation techniques.

Two chiral stationary phases virtually reproducing the Nautilus-R column were modeled in silico to study the enantiorecognition mechanism of some selected dipeptides, taking into consideration the two different anchoring alternatives to the silica layer involving the two ristocetin A amino groups. A mobile phase composed of water-methanol (40:60, v/v) was included in the system. The analyses of the trajectories supported the experimental L(LL) View Article and Find Full Text PDF

Moral Judgements on the Actions of Self-Driving Cars and Human Drivers in Dilemma Situations From Different Perspectives.

Self-driving cars have the potential to greatly improve public safety. However, their introduction onto public roads must overcome both ethical and technical challenges. To further understand the ethical issues of introducing self-driving cars, we conducted two moral judgement studies investigating potential differences in the moral norms applied to human drivers and self-driving cars.

[Alveolar bone and dental arch defects fulfillment in cleft lip and palate patients].

Nine cleft lip and palate patients aged 17-32 years were included in the study, all having significant maxilla alveolar bone defects. Oral rehabilitation was possible by means of bone augmentation with iliac crest graft, soft tissue plasty and subsequent dental implantation (3 to 6 months after first-step procedures).

[Analysis of genomic polymorphism in leptospira by polymerase chain reaction with random primers].

A test system for genetic typing of Leptospirae is developed, based on the polymerase chain reaction (PCR) with arbitrary primers. Thirteen strains of 4 Leptospira species were examined: L. interrogans, L.