Publications by authors named "M A Pelli"

Along with physical changes, psychological changes are detectable in patients with COVID-19. In these patients, the stressful experience of intensive care unit (ICU) hospitalization may aggravate psychological conditions. Our study examines the short- and long-term psychological consequences of COVID-19 in ICU patients.

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Article Synopsis
  • A study explored the effectiveness of multimodal opioid-free anesthesia (OFA) using ketamine, magnesium, and clonidine in managing postoperative pain for breast cancer surgery, compared to traditional opioid-inclusive anesthesia (OIA).
  • The results indicated that patients in the OFA group experienced lower levels of postoperative pain, required fewer additional analgesics, and had a reduced incidence of postoperative nausea and vomiting (PONV) compared to those in the OIA group.
  • Overall, the findings suggest that using this OFA approach could provide improved outcomes for patients undergoing quadrantectomy while maintaining similar levels of patient satisfaction.
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The anesthetic management of adult patient with Down syndrome (DS) can be challenging due to poor patient cooperation, age-related comorbidities, and a possible difficult airway. Thoracic anesthesia requires an advanced airway management; thus, treatment of DS patients can be particularly demanding. An accurate preoperative assessment is paramount in order to plan a well-designed perioperative strategy in advance.

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Introduction: Decompression sickness (DCS) is considered a 'bubble disease'. Intravascular bubbles activate inflammatory responses associated with endothelial dysfunction. Breathing gas has been proposed as a potential risk factor but this is inadequately studied.

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Teicoplanin has a potential antiviral activity expressed against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and was suggested as a complementary option to treat coronavirus disease 2019 (COVID-19) patients. In this multicentric, retrospective, observational research the aim was to evaluate the impact of teicoplanin on the course of COVID-19 in critically ill patients. Fifty-five patients with severe COVID-19, hospitalized in the intensive care units (ICUs) and treated with best available therapy were retrospectively analysed.

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