Predictors of glycaemic improvement in children and young adults with type 1 diabetes and very elevated HbA1c using the MiniMed 780G system.

Aims: This study aimed to identify key factors with the greatest influence on glycaemic outcomes in young individuals with type 1 diabetes (T1D) and very elevated glycaemia after 3 months of automated insulin delivery (AID).

Materials And Methods: Data were combined and analysed from two separate and previously published studies with similar inclusion criteria assessing AID (MiniMed 780G) efficacy among young individuals naïve to AID (aged 7-25 years) with glycated haemoglobin A1c (HbA1c) ≥69 mmol/mol (≥8.5%).

Correction: Acceptability and feasibility of HIV self-testing among transgender people in Larkana, Pakistan: Results from a pilot project.

[This corrects the article DOI: 10.1371/journal.pone.

Welfare assessment of broiler chickens at live bird market of Chattogram in Bangladesh.

Objective: This study aimed to assess the welfare conditions of broiler chickens in the live bird markets (LBMs) in Bangladesh.

Materials And Methods: A total of fifty broiler outlets were studied in 10 LBMs of Chattogram, Bangladesh. A total of 10 chickens were observed to check the welfare issues during slaughter from each outlet ( = 500).

Community-led interventions to re-engage people living with HIV into care in Pakistan.

Background: By 2021, Pakistan had an estimated 210 000 people living with HIV (PLHIV), and 27% of those initiated into treatment in 2020 had disengaged from care within one year.

Aim: We assessed the effectiveness of an intervention to re-engage PLHIV lost to follow-up into care in Pakistan.

Methods: Between September 2020 and May 2021, the Association of People Living with HIV (APLHIV) implemented a search and rescue intervention for PLHIV lost to follow-up in 2 large treatment centres in Pakistan.

Molecular docking, ADME properties and synthesis of thiophene sulfonamide derivatives.

This study investigates the drug-like properties of target molecules containing thiophene sulfonamide groups using computational molecular docking techniques. The binding interactions of these derivatives were assessed using protein 2NSD (Enoyl acyl carrier protein reductase InhA, complexed with N-(4-methylbenzoyl)-4-benzylpiperidine, PDB DOI: 10.2210/pdb2NSD/pdb) as the receptor.