Publications by authors named "M A Papadopoulos"
There is increasing interest in monitoring pressure from the injured spinal cord to guide the management of patients with acute, severe traumatic spinal cord injuries (TSCI). This is analogous to monitoring intracranial pressure and cerebral perfusion pressure in traumatic brain injury (TBI). Here, we explore key concepts in this field and novel therapies that are emerging from these ideas.
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- APU1 and APU2 exhibit different levels of virulence in chickens, with APU1 demonstrating greater fecundity and upregulation of specific genes identified through RNA-seq and confirmed by quantitative RT-PCR.
- The genes (EMWEY 23530 and EMWEY 48910) were cloned and expressed, showing consistent sizes with predictions, and their proteins were analyzed via immunostaining and 2D gel blots, revealing higher expression levels in APU1 relative to APU2.
- Immunofluorescence staining indicated the location of proteins Emax p33.5 and Emax p41 in oocysts, suggesting that these proteins may underlie phenotypic differences and higher
The accurate diagnosis of bacterial infections remains a critical challenge in clinical practice. Traditional imaging modalities like computed tomography (CT) and magnetic resonance imaging (MRI) often fail to distinguish bacterial infections from sterile inflammation. Nuclear medicine, such as technetium-99m (Tc) radiopharmaceuticals, offers a promising alternative due to its ideal characteristics.
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- The study compares the effectiveness of home-based vs. office-based phototherapy for psoriasis, highlighting that while office therapy is cost-effective, it’s often hard to access compared to the more patient-preferred home therapy, which lacks sufficient clinical data, especially for those with darker skin.
- Conducted across 42 dermatology practices in the US, the trial involved 783 participants aged 12 and older with psoriasis, who were randomly assigned to either home or office phototherapy for 12 weeks, followed by another 12 weeks of observation.
- Results showed that home phototherapy led to better skin clearance and quality of life improvements, with 32.8% of participants achieving clear skin compared to
Corticotropin-releasing factor (CRF) is a key neuropeptide hormone that is secreted from the hypothalamus. It is the master hormone of the HPA axis, which orchestrates the physiological and behavioral responses to stress. Many disorders, including anxiety, depression, addiction relapse, and others, are related to over-activation of this system.
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