[Complex assessment of esophageal acidification and motor function in patients with Barrett's esophagus on antisecretory therapy].

Aim: To determine predictors of insufficient effectiveness of proton pump inhibitors based on the parameters of 24-hours pH-impedance and features of motor function of the esophagus in patients with Barrett's esophagus.

Materials And Methods: 17 patients with histologically verified Barrett's esophagus undergoing acid-suppressive therapy were examined. All patients underwent 24-hours pH-impedance and high-resolution esophageal manometry.

[The duration of hormone synthesis by cultures of human fetal endocrine cells].

It is stated as possible to cultivate and accumulate endocrine cells by regular passages in vitro over a long period of time. In this case endocrine cells of human fetus don't loose the ability to synthesize hormone. Such cultures can be used to study some general-biological problems out of influence of the neurohumoral organism factors.

[The morphofunctional properties of the interstitial endocrinocytes of human testes cultured in vitro].

The authors demonstrated the possibility to obtain the pure culture of interstitial endocrinocytes from the testis of human embryo aged 14-24 weeks. Morphofunctional study of in vitro cultures revealed the presence of interstitial endocrinocytes in the monolayer. The ability of these cells to synthesize hormones preserved within the whole period of cultivation was confirmed by an isotope radiology method.

[Correction of alloxan diabetes in rats using xenotransplantation of passaged cultures of human embryonic pancreatic beta cells].

The authors present experimental data on the antidiabetic effect of passaged human embryonic pancreatic beta-cells in their xenotransplantation to rats with alloxan diabetes. Intra-abdominal xenotransplantation of such cultures results in a stable compensation of glycemia in rats with experimental diabetes. These data are important in terms of a possibility to use passaged human embryonic pancreatic beta-cells for transplantation to patients with diabetes mellitus.