Symmetric 3-periodic polycatenanes: catenated rings, polyhedra and rods.

We report symmetric (vertex- and arc-transitive) embeddings of catenated rings, polyhedra and rods. Linked triangles form infinite families of structures, and we limit this report to only structures with each ring linked to three or six others. For linked squares, hexagons, tetrahedra, octahedra, cubes and rods, only a small number of symmetric structures were found, and all are reported.

Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus.

Brain-resident macrophages, microglia, have been proposed to have an active role in synaptic refinement and maturation, influencing plasticity and circuit-level connectivity. Here we show that several neurodevelopmental processes previously attributed to microglia can proceed without them. Using a genetically modified mouse that lacks microglia (Csf1r), we find that intrinsic properties, synapse number and synaptic maturation are largely normal in the hippocampal CA1 region and somatosensory cortex at stages where microglia have been implicated.

A pain research strategy for Europe: A European survey and position paper of the European Pain Federation EFIC.

Background: Pain is the leading cause of disability and reduced quality of life worldwide. Despite the increasing burden for patients and healthcare systems, pain research remains underfunded and under focused. Having stakeholders identify and prioritize areas that need urgent attention in the field will help focus funding topics, reduce 'research waste', improve the effectiveness of pain research and therapy and promote the uptake of research evidence.

Two-Periodic MoS-Type Metal-Organic Frameworks with Intrinsic Intralayer Porosity for High-Capacity Water Sorption.

2D metal-organic frameworks (2D-MOFs) are an important class of functional porous materials. However, the low porosity and surface area of 2D-MOFs have greatly limited their functionalities and applications. Herein, the rational synthesis of a class of mos-MOFs with molybdenum disulfide (mos) net based on the assembly of trinuclear metal clusters and 3-connected tripodal organic ligands is reported.

Readiness of primary healthcare and community markets for joint delivery of cardiovascular disease prevention services in Kenya: an observational feasibility study of Health Kiosks in Markets (HEKIMA).

Objectives: The increasing burden of cardiovascular diseases (CVDs) in Kenya threatens its healthcare system. There is a need for innovative models that improve equitable access to CVD prevention services. Community markets are social establishments with untapped potential to promote public health.