Publications by authors named "M A Medina Urquiza"

Article Synopsis
  • The study investigates how the reason for hospital admission affects adverse health outcomes in older adults undergoing geriatric rehabilitation.
  • It analyzes data from patients with orthogeriatric conditions and hospital-associated deconditioning to identify predictors like cognitive and nutritional health status.
  • Results indicate that specific assessments, like the Mini-Mental State Examination and Short Physical Performance Battery, significantly influence the likelihood of hospital readmission, institutionalization, and mortality.
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Article Synopsis
  • Integrins are crucial cell receptors that play a role in cell proliferation and are linked to various metabolic pathways; their downregulation during development and overexpression in adults are associated with diseases like cancer.
  • The review examines the structures of integrin-peptide ligand complexes to understand the binding mechanisms and the specificity of these interactions, which is important for developing new peptide-based cancer therapies.
  • Focused on complexes such as α5β1, αIIbβ3, αvβ3, αvβ6, and αvβ8, the article highlights how these integrins are linked to poor cancer prognosis, making them key targets for diagnosis and treatment.
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Article Synopsis
  • Digital technologies and open innovation have led to the creation of virtual organizations, exemplified by the International Natural Product Sciences Taskforce (INPST), established in 2018 for collaboration in natural product research.
  • The INPST utilized Twitter for a week-long networking event in June 2021, using the hashtag #INPST to facilitate interactions among participants.
  • Analysis of the event revealed 6,036 tweets from 686 users, resulting in over 65 million impressions, highlighting Twitter's effectiveness for hosting international biomedical research discussions.
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Article Synopsis
  • The study examines the relationship between the Charlson Comorbidity Index (CCI), nutritional status, and physical function in hospitalized older adults to see if malnutrition or poor physical function relates to higher CCI scores.
  • It involved 597 older patients, assessing their CCI, nutritional state with the Mini Nutritional Assessment-Short Form, and physical capability through handgrip strength and the Short Physical Performance Battery.
  • Results showed that better nutrition and physical performance correlated with lower CCI scores, and individuals at risk of malnutrition or frailty had a significantly higher risk of severe comorbidity.
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Background & Aims: Malnutrition and poor physical performance are highly prevalent within hospitalized older adults, and both have in common the loss of muscle mass. Likewise, there is growing interest in identifying markers of physical performance, other than just measuring muscle mass, that might be useful for managing malnutrition. This study aimed to (i) characterize the physical condition of hospitalized older adults in comparison to previously published reference percentile values of same age adults and (ii) to examine the association between the nutritional status and physical performance of older inpatients.

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