Zh Nevrol Psikhiatr Im S S Korsakova
March 2025
Objective: To study clinical and immunological relationships in patients with early schizophrenia during remission.
Material And Methods: Forty-eight patients (53% females and 47% males) were examined at the initial stage of schizophrenia during remission (age 28.3±5.
Background: The review analyzes the possible role of autoimmune processes in the pathogenesis of schizophrenia and the evolution of concepts on this issue from its origin to the present.
Results: Risks of autoimmune processes causing schizophrenia are associated with several factors: an impaired functioning of dopaminergic and glutamatergic systems in the brain, kynurenine pathway disorder with overproduction of quinolinic, anthranilic, and kynurenic acids (possibly altering both neurons and T-regulators), increased intestinal permeability, as well as food antigens' effects, stress and infections with various pathogens at different stages of ontogenesis. An increase in the levels of proinflammatory cytokines and chemokines as well as a decrease in the levels of anti-inflammatory ones also may contribute to schizophrenia risks.
We present incoherent quasi-elastic neutron scattering measurements in a wave vector transfer range from 0.4 Å(-1) to 1.6Å (-1) on liquid n-hexane confined in cylindrical, parallel-aligned nanochannels of 6 nm mean diameter and 260 μm length in monolithic, mesoporous silicon.
View Article and Find Full Text PDFA bismuth-doped-pure-silica holey fiber is fabricated using a fiber preform made by the furnace chemical vapor deposition method. The spectroscopic properties of the fiber are studied, and laser action at λ=1450 nm with an efficiency of 12% is demonstrated.
View Article and Find Full Text PDFWe have studied the microscopic dynamics of a glass-forming liquid in the soft confinement formed by microemulsion droplets using inelastic neutron scattering. The confined liquid was propylene glycol, the outer, hydrophobic phase was decalin, and the surfactant sodium dioctylsulfosuccinate (AOT) with the same composition used before with other spectroscopic methods [L.-M.
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