Publications by authors named "M A Martinez-Leon"

The World Health Organization reported that tuberculosis remains on the list of the top ten threats to public health worldwide. Among the main causes is the limited effectiveness of treatments due to the emergence of resistant strains of . One of the main drug targets studied to combat is DNA gyrase, the only enzyme responsible for regulating DNA topology in this specie and considered essential in all bacteria.

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  • The study aimed to evaluate the effectiveness of endoscopic third ventriculostomy (ETV) for treating pediatric chronic communicating congenital hydrocephalus (CCCH).
  • A retrospective analysis included 11 children, tracking their symptoms, surgery details, and follow-up results, focusing on clinical and radiological improvements post-surgery.
  • Results indicated that ETV was generally successful, with most patients showing significant improvement and only three requiring additional shunt placement over an average follow-up of nearly 36 months.
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  • The ImageKids study aimed to create and validate the PEMPAC index for assessing perianal Crohn's disease in children using MRI scans across 21 global sites.
  • A total of 80 children were involved, with specific criteria for evaluating various aspects of their condition, leading to two statistical models that correlated well with existing assessment tools.
  • The study concluded that the PEMPAC index effectively measures disease severity in children, and the adult Van Assche index can also be applied reliably in this pediatric population.
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