Publications by authors named "M A M J van Zandvoort"

Nitrous oxide (NO) emissions from wastewater treatment plants (WWTPs) exhibit significant seasonal variability, making accurate predictions with conventional biokinetic models difficult due to complex and poorly understood biochemical processes. This study addresses these challenges by exploring data-driven alternatives, using long short-term memory (LSTM) based encoder-decoder models as basis. The models were developed for future integration into a model predictive control framework, aiming to reduce NO emissions by forecasting these over varying prediction horizons.

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Background: The increasing incidence of brain metastases (BMs) and improved survival rates underscore the necessity to investigate the effects of treatments on individuals. The aim of this study was to evaluate the individual trajectories of subjective and objective cognitive performance after radiotherapy in patients with BMs.

Methods: The study population consisted of adult patients with BMs referred for radiotherapy.

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Tissue engineering is a steadily growing field of research due to its wide-ranging applicability in the field of regenerative medicine. Application-dependent mechanical properties of a scaffold material as well as its biocompatibility and tailored functionality represent particular challenges. Here the properties of fibrin-based hydrogels reinforced by functional cytocompatible poly(N-vinylcaprolactam)-based (PVCL) microgels are studied and evaluated.

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Background: A significant proportion of patients and informal caregivers favor an active role in decisions concerning their health. Simultaneously, governments aim to shift treatment from a professional care setting to a community setting, in light of an ageing population, a decreasing number of health workers and allocation of scarce resources. This transition of care solicits patients' and informal caregivers' ability to self-manage.

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Article Synopsis
  • Atherosclerotic plaques' destabilization is linked to the presence of specific microvessels, which might be leaky, although evidence is still needed.
  • This study aimed to find key molecular drivers of dysfunction in these vessels by analyzing transcriptome data from human atherosclerotic lesions and identifying crucial genes related to microvascular density and inflammation.
  • The research highlighted Spectrin Beta Non-Erythrocytic 1 (sptbn1) as a central gene that, when silenced, increased vascular permeability and inflammation, suggesting it plays a significant role in regulating the leaky characteristics of plaque microvessels related to cardiovascular disease.
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