What women want from hormone replacement therapy: results of an international survey.

Objectives: To find out what women in France, Germany and the UK want from hormone replacement therapy (HRT).

Methods: A questionnaire sent to almost 2000 women in France, Germany and the UK followed up by more detailed interviews with 100 women from each country.

Results: From the questionnaire sent to 1871 women aged 48-55 years in France, Germany and the UK, it was found that 72% had not used HRT.

Quality of life after the menopause: influence of hormonal replacement therapy.

Objective: Our purpose was to demonstrate the clinical efficacy and effect of hormone replacement therapy in menopause on quality of life.

Study Design: A randomized, open, 6-month comparison of hormone replacement therapy (estradiol transdermal system [Estraderm TTS] plus chlormadinone) and symptomatic treatment (verapipride) was performed. Analysis was by intention to treat.

[Respective importance of the different risk factors for osteoporosis].

Among the factors which influence accumulation of bone mass, genetic factors related to race and family are preponderant: they account for approximately 80% of the variance observed in adulthood. At puberty, nutritional factors and physical activity modulate the accumulation of bone and determine whether or not optimal bone mass is achieved. In women, estrogen deprivation following menopause, and also more minor disorders of gonad function, are the main causes of decreased bone mass; their respective contributions are analyzed.