Publications by authors named "M A Lilly"
Article Synopsis
- * Researchers used a specialized magnetic microscope to image the magnetic fields from many isolated SPIONs, discovering distinct magnetization patterns that traditional methods wouldn't reveal.
- * The study also recorded SPION relaxation times after an applied magnetic field was turned off, showing a wide range of characteristics among the nanoparticles, indicating their varied behavior and potential for further nanomagnetism research.
Article Synopsis
- TORC1 is a key protein complex that promotes growth and suppresses breakdown of cellular components, and its dysfunction is linked to serious health issues like cancer and neurodegenerative diseases.
- The GATOR complex regulates TORC1, with GATOR1 inhibiting its activity and GATOR2 counteracting GATOR1, but the specific mechanisms of GATOR2 are still not fully understood.
- Recent studies in fruit flies (Drosophila) have revealed new roles for GATOR2, including its influence on autophagy and nutrient sensing, emphasizing the importance of whole-animal models in uncovering these complex biological interactions.
Habitat loss and forest fragmentation are often linked to increased pathogen transmission, but the extent to which habitat isolation and landscape connectivity affect disease dynamics through movement of disease vectors and reservoir hosts has not been well examined. Tick-borne diseases are the most prevalent vector-borne diseases in the United States and on the West Coast, is one of the most epidemiologically important vectors. We investigated the impacts of habitat fragmentation on pathogens transmitted by and sought to disentangle the effects of wildlife communities and landscape metrics predictive of pathogen diversity, prevalence and distribution.
View Article and Find Full Text PDFThe recurring spillover of pathogenic coronaviruses and demonstrated capacity of sarbecoviruses, such SARS-CoV-2, to rapidly evolve in humans underscores the need to better understand immune responses to this virus family. For this purpose, we characterized the functional breadth and potency of antibodies targeting the receptor binding domain (RBD) of the spike glycoprotein that exhibited cross-reactivity against SARS-CoV-2 variants, SARS-CoV-1 and sarbecoviruses from diverse clades and animal origins with spillover potential. One neutralizing antibody, C68.
View Article and Find Full Text PDFObjectives: The goal of this study was to gather information on treatment approaches and trends for the treatment of non-obstructive feline idiopathic cystitis (FIC).
Methods: An internet-based survey of veterinarians was conducted focusing on outpatient treatment approaches for cats that are stable, not obstructed and that exhibit lower urinary signs suspected to be due to FIC, where other causes (eg, urolithiasis, urinary tract infection, other) have been ruled out.
Results: A total of 606 veterinarians submitted complete surveys for inclusion.