Publications by authors named "M A Lemaire"

Article Synopsis
  • - Cell-free placental DNA (cfpDNA) is found in the blood of pregnant women and can be used to study the placenta without invasive procedures.
  • - CfpDNA has proven useful in noninvasive prenatal testing (NIPT), but our understanding of its biology is still limited, which hampers further research and applications.
  • - This review aims to summarize what we know about cfpDNA, identify knowledge gaps, and suggest future research avenues to enhance its clinical utility.
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Introduction: Non-small cell lung cancers (NSCLC) are the most common lung cancers, withpeak incidence at 65years of age. These cancers rarely occur before the age of 40.

Methods: Based on an illustrative clinical case, a systematic review of the literature was conducted to study the epidemiological, clinical, histological, and biological characteristics of NSCLC in adults under 40years of age.

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We describe the unexpected challenges pediatricians may experience when children conceived with assisted reproduction are diagnosed with a rare genetic condition. A local case series triggered a dialogue between many stakeholders with varied expertise. Indeed, diagnosing a genetic disease in a child conceived by embryo, egg, or sperm donation is becoming more common now that genetic testing and in vitro fertilization (IVF) are readily accessible.

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Objectives: The aim of the study was to evaluate the effects on infant growth and tolerance of a Test infant formula based on a novel whey extraction and demineralization process, compared to a Standard formula and a breastfed reference arm.

Methods: Healthy term infants (n = 61) aged up to 21 days were randomized to Test or Control formula. A breastfed group (n = 39) served as a reference.

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Background: Infant formulas (IFs), the only adequate substitute to human milk, are complex matrices that require numerous ingredients and processing steps that may impact protein digestion and subsequent amino acid (AA) absorption.

Objectives: The objective was to understand the impact of the protein ingredient quality within IFs on postprandial plasma AA profiles.

Methods: Four isonitrogenous and isocaloric IFs were produced at a semi-industrial scale using whey proteins from different origins (cheese compared with ideal whey) and denaturation levels (IF-A, -B, -C), and caseins with different supramolecular organizations (IF-C, -D).

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