Publications by authors named "M A Krol"
Optoelectronic and spinoptronic technologies benefit from flexible and tunable coherent light sources combining the best properties of nano- and material-engineering to achieve favorable properties such as chiral lasing and low threshold nonlinearities. In this work we demonstrate an electrically wavelength- and polarization-tunable room temperature polariton laser due to emerging photonic spin-orbit coupling. For this purpose, we design an optical cavity filled with both birefringent nematic liquid crystal and an inorganic perovskite.
View Article and Find Full Text PDFExploring the non-Hermitian properties of semiconductor materials for optical applications is at the forefront of photonic research. However, the selection of appropriate systems to implement such photonic devices remains a topic of debate. In this work, we demonstrate that a perovskite crystal, characterized by its easy and low-cost manufacturing, when placed between two distributed Bragg reflectors with an air gap, can form a natural double microcavity.
View Article and Find Full Text PDFHemoglobin (Hb) performs its physiological function within the erythrocyte. Extracellular Hb has prooxidative and proinflammatory properties and is therefore sequestered by haptoglobin and bound by the CD163 receptor on macrophages. In the present study, we demonstrate a novel process of Hb uptake by macrophages independent of haptoglobin and CD163.
View Article and Find Full Text PDFArticle Synopsis
- Modern lifestyle diseases like diabetes and obesity affect millions globally, with GLP-1 receptor agonists (GLP-1RAs) emerging as significant treatments due to their broader influence on metabolic disorders.
- Evidence suggests GLP-1RAs might impact the thyroid and pancreas, raising concerns over their long-term safety, particularly regarding pancreatitis and thyroid tumors.
- The review highlights the importance of frequent monitoring for patients using GLP-1RAs, especially those at higher risk for these conditions.
Article Synopsis
- Membrane transporters are proteins found in various tissues that control the movement of ions, drugs, and other substances in the body.
- ABC and SLC drug transporters are especially important for how drugs are absorbed, distributed, and eliminated, directly affecting their effectiveness and interactions in the body.
- The function and expression of these transporters can be influenced by factors like gut microbiome composition and concurrent medications, and this review will highlight their role in drug metabolism and their potential as targets for new therapies.