Publications by authors named "M A Kiriukova"

Aim: To evaluate the possibilities of post-processing of multidetector computed tomography (CT) results in the non-invasive diagnosis of pancreatic fibrosis (PF).

Materials And Methods: The study included 165 patients aged 57.91±13.

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Background & Aims: Autoimmune pancreatitis (AIP) is an immune-mediated disease of the pancreas with distinct pathophysiology and manifestations. Our aims were to characterize type 1 AIP in a large pan-European cohort and study the effectiveness of current treatment regimens.

Methods: We retrospectively analyzed adults diagnosed since 2005 with type 1 or not-otherwise-specified AIP in 42 European university hospitals.

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Article Synopsis
  • The study investigates the relevance of biopsies from the incisura angularis in determining the risk of gastric cancer in patients with chronic gastritis using the OLGA system for assessment.
  • A total of 718 patients were examined, aged 20 to 84, and categorized based on the presence of autoimmune gastritis markers, resulting in three distinct patient groups.
  • Results showed that grade II inflammatory changes were prevalent (72.3%) across all groups, with severe chronic gastritis activity most common in patients with non-autoimmune gastritis, and these findings remained consistent even when excluding the incisura angularis biopsy.
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  • Pancreatic fibrosis (PF) is key in chronic pancreatitis and this study examined its relationship with various factors in pancreatic specimens from 74 patients.
  • Significant differences were found in imaging parameters (like unenhanced pancreas density and contrast enhancement ratio) based on fibrosis grades and inflammation indicators in the tissue.
  • Blood levels of fibronectin and hyaluronic acid showed correlations with different aspects of fibrosis, suggesting that these and imaging parameters could aid in non-invasive diagnosis of PF.
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Unlabelled: Malnutrition and cachexia are common in patients with advanced pancreatic ductal adenocarcinoma (PDAC) and have a significant influence on the tolerance and response to treatments. If timely identified, malnourished PDAC patients could be treated to increase their capacity to complete the planned treatments and, therefore, possibly, improve their efficacy. The aim of this study is to assess the impact of nutritional status, pancreatic exocrine insufficiency (PEI), and other clinical factors on patient outcomes in patients with advanced PDAC.

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