Establishing normal interocular symmetry range for macular optical coherence tomography parameters in healthy children.

Objective: The study aimed to evaluate the interocular symmetry of macular sublayer thickness among healthy children aged 6-12 years.

Methods: The Shiraz Pediatric Eye Study included 500 randomly selected children who underwent SD-OCT of the macula and optical biometry using the IOLMaster-500. Exclusion criteria involved ocular abnormalities or axial lengths outside the 21.

Canadian Highly Sensitized Patient Program Report: A 1000 Kidney Transplants Story.

Purpose: Highly sensitized patients (HSPs) with kidney failure have limited access to kidney transplantation and poorer post-transplant outcomes. Prioritizing HSPs in kidney allocation systems and expanding the pool of deceased donors available to them has helped to reduce their wait times for transplant and enhanced post-transplant outcomes. The Canadian HSP Program was established by Canadian Blood Services in collaboration with provincial organ donation and transplantation programs throughout the country to increase transplant opportunities for transplant candidates needing very specific matches from deceased kidney donors.

HMG-CoA reductase inhibitor simvastatin ameliorates trimethyltin neurotoxicity and cognitive impairment through reversal of Alzheimer's-associated markers.

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder in elderly. The neurotoxicant trimethyltin (TMT) induces neurodegenerative changes, as observed in AD. The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor simvastatin (SV) has shown protective and promising therapeutic effects in neurological disorders such as AD and Parkinson's disease.

Clinicopathological Features of Frontal Fibrosing Alopecia (FFA) in 26 females: A Retrospective Study.

Background & Objective: FFA usually has a gradual subtle course and might be overlooked by physicians or misdiagnosed with other types of hair loss including androgenetic alopecia, traction alopecia, and other types of patterned alopecia. In this study, we described clinicopathological features of patients with FFA referring for skin biopsy.

Methods: This is a retrospective cross-sectional study on 26 patients with a diagnosis of FFA based on clinicopathological features.