Publications by authors named "M A Ichou"

Prior research has found that immigrants are often overeducated: their educational attainment is higher than required or commonly observed in their occupation. Yet, less is known about the education-occupation mismatch among immigrants' children and grandchildren (the second and third generations). Using the French Trajectories and Origins 2 (TeO2, 2019-2020) survey, we test theoretically grounded hypotheses on the level of vertical (educational attainment) and horizontal (field of study) mismatch in the first, second, and third generations as well as on the mechanisms underlying the mismatch.

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Background: This review article aims to investigate the prevalence and spectrum of rat sarcoma (RAS) and V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF) mutations, and their connection with geographical location, clinicopathological features, and other relevant factors in colorectal cancer (CRC) patients in the Middle East.

Methods: A systematic literature review, employing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework, was conducted to investigate the association between the frequency of relevant mutations and the descriptive clinicopathological characteristics of CRC patients. Multiple electronic databases, including PubMed, Science Direct, Web of Science, Scopus, and Google Scholar, were searched to analyze the relevant literature.

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Purpose: The primary aim of this study is to determine the relationship between tumor-stroma ratio (TSR) and traditional prognostic factors in luminal early breast cancer in women treated at the medical oncology department of the military hospital of Rabat in Morocco.

Methods: A retrospective study was performed on primary invasive ER+/HER2- breast cancer in the period from January 1st, 2019 to December 31st, 2019. Prognostic factors included age, tumour size, lymph nodes status, Scarff-Bloom-Richardson grading, lymphovascular invasion (LVI), Ki67 and the stage of the disease.

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Article Synopsis
  • The research investigates whether the 'immigrant health paradox,' where immigrants generally have better health outcomes, also applies to the birth weights of their children compared to native-born children in Western Europe and Australia.
  • Data from five major studies with thousands of participants was used to compare birth weights of infants born to immigrant parents versus native parents.
  • Findings revealed mixed results: children of immigrants in France and Australia had higher birth weights, while those in the UK and the Netherlands had lower birth weights, with smoking during pregnancy identified as a possible factor influencing these differences.
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Background: Mutations in RAS (KRAS, NRAS) and BRAF genes are the main biomarker predicting response to anti-EGFR monoclonal antibodies in targeted therapy in colorectal cancer (CRC).

Objective: Our study aims to evaluate the frequencies of KRAS, NRAS and BRAF mutations and their possible associations with clinico-pathological features in CRC patients from Morocco.

Methods: DNA was extracted from 80 FFPE samples using the QIAamp DNA FFPE-kit.

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