Factors associated with undernutrition among pregnant women in Chiro district, eastern Ethiopia.

Background: Undernutrition denotes inadequate intake of energy and nutrients to meet one's optimal needs. Pregnant women are at an increased risk of undernutrition due to the added nutritional demand for fetal growth and development. Updated evidence is important for monitoring progress and informing healthcare decisions.

Multi-cohort cerebrospinal fluid proteomics identifies robust molecular signatures across the Alzheimer disease continuum.

Changes in β-amyloid (Aβ) and hyperphosphorylated tau (T) in brain and cerebrospinal fluid (CSF) precede Alzheimer's disease (AD) symptoms, making the CSF proteome a potential avenue to understand disease pathophysiology and facilitate reliable diagnostics and therapies. Using the AT framework and a three-stage study design (discovery, replication, and meta-analysis), we identified 2,173 analytes (2,029 unique proteins) dysregulated in AD. Of these, 865 (43%) were previously reported, and 1,164 (57%) are novel.

Advancing green and white assessment: DFT-assisted spectrofluorimetry for accurate favipiravir quantification in human plasma.

Recently, the recognition of computational chemistry potential is growing, because of its applicability for design of substances and studying their properties using computer programs and modelling approaches that help solve various problems. Computational chemistry is involved in the design of advanced fluorescent probes which can be employed in sensing of various analytes. Favipiravir (FVR) is an antiviral drug recommended for the treatment of COVID-19, known for its broad-spectrum activity against RNA viruses by inhibiting viral RNA-dependent RNA polymerase.

Efficacy of Lacticaseibacillus rhamnosus probiotic strains in treating chromate induced dermatitis.

Chromate induced dermatitis is a significant occupational health concern. Chromate (Cr) resistant Lacticaseibacillus rhamnosus strains were isolated from commercial probiotic sachets PREPRO and HiFLORA. Among 13 Cr-resistant bacterial isolates, six were selected based on high chromate resistance at 500 ug/ml.

A masked study to differentiate in vivo confocal microscopic features of Pythium insidiosum and fungal filaments.

Purpose: To describe in vivo confocal microscopic features of Pythium insidiosum in patients with Pythium keratitis and compare with those observed in fungal keratitis.

Method: We collected in vivo confocal images of the cornea from patients with microbiologically confirmed Pythium and fungal keratitis, analysing five putative distinguishing features: filament width (broad or thin), granularity within the filament (present or absent), filament continuity or traceability, the presence or absence of loops, and the double track sign. Three masked observers were shown images with concealed identities and tasked with detecting Pythium filaments.