Epidemiological Characteristics of Mumps Cases in the Kingdom of Bahrain From 2012 to 2022.

Introduction: Mumps is a vaccine-preventable disease caused by the paramyxovirus affecting the salivary gland and may be complicated by orchitis, oophoritis, and encephalitis. This study aims to describe the epidemiology, clinical presentation, and transmission of mumps cases in the Kingdom of Bahrain between 2012 and 2022.

Methodology: A retrospective cross-sectional study was conducted using national surveillance data of confirmed mumps cases, including all age groups and both Bahraini and non-Bahraini nationals, from January 2012 to December 2022.

HDAC1 and HDAC2 Are Involved in Influenza A Virus-Induced Nuclear Translocation of Ectopically Expressed STAT3-GFP.

Influenza A virus (IAV) remains a pandemic threat. Particularly, the evolution and increased interspecies and intercontinental transmission of avian IAV H5N1 subtype highlight the importance of continuously studying the IAV and identifying the determinants of its pathogenesis. Host innate antiviral response is the first line of defense against IAV infection, and the transcription factor, the signal transducer and activator of transcription 3 (STAT3), has emerged as a critical component of this response.

Development of a curcumin-piperine nanoparticle system using dissolving microneedles for transdermal drug delivery in malaria treatment: In vitro evaluation.

The combination of the active compounds curcumin and piperine (CP) is effective as an antimalarial; however, the solubility and bioavailability of CP are very low. This study aims to formulate CP in nanoparticles (NP), which are then fabricated into dissolving microneedles (DMN). The NPs were prepared with a concentration ratio of CP-Chitosan-So.

Adult Mediastinal Lymphangioma Presenting As Persistent Chest Pain: A Case Report.

Mediastinal lymphangiomas are rare benign tumors arising from lymphatic system malformations, most commonly seen in pediatric populations. In adults, they are exceedingly rare and present diagnostic challenges due to nonspecific symptoms and imaging overlap with other mediastinal masses. Diagnosis is typically based on imaging, including CT and MRI, with histopathology confirming the diagnosis.