Publications by authors named "M A Howald"

Oreste Ghislaba's powerful vision and actions to make Switzerland a world-leading hub in biotechnology are described. He recognised the great potential for innovation in biotechnology and was able to communicate this to stakeholders in academia, industry and politics. He was instrumental in the creation of organisations such as Swiss Biotech Association, the CTI, the SATW, TA-Swiss, and the Swiss Industrial Biocatalysis Consortium that helped to create the Swiss biotech hub.

View Article and Find Full Text PDF

Fine particle dose (FPD) is a critical quality attribute for orally inhaled products (OIPs). The abbreviated impactor measurement (AIM) concept simplifies its measurement, provided there is a validated understanding of the relationship with the full resolution pharmacopoeial impactor (PIM) data for a given product. This multi-center study compared fine particle dose determined using AIM and PIM for five dry powder inhaler (DPIs) and two pressurized metered-dose inhaler (pMDI) products, one of which included a valved holding chamber (VHC).

View Article and Find Full Text PDF

In order to investigate stress responses of horses in walkers with and without electricity, 12 horses were trained during 3 weeks in a horse walker with and without the use of electricity (3.7 kV). To evaluate the stress response, cortisol levels in the blood were measured, the heart rate was monitored using the Polar® system and the behaviour was evaluated.

View Article and Find Full Text PDF

The production of B-cell specific alloantisera by lymphocyte transfusion between class I matched, MLR positive goats is described. Furthermore, the usefulness of preceding IEF typing is demonstrated in the selection of immunization pairs. After suitable absorptions and cluster analysis the detected B-cell specific antigens were designated BeD1-BeD6.

View Article and Find Full Text PDF