Publications by authors named "M A Habeeb Muhammed"
Article Synopsis
- The study investigates the inhibitory effects of R. cathartica L. plant extract on the Quorum Sensing (QS) system in various bacteria using molecular modeling techniques.
- The methanol extract demonstrated antimicrobial activity, especially against Gram-positive and Gram-negative bacteria, with noticeable effects on P. aeruginosa.
- Phytochemical analysis identified kaempferol as the primary component, which was shown to bind to QS system receptors and potentially offer a new eco-friendly antibacterial treatment.
Gut-derived appetite regulating hormones across the anorexia nervosa spectrum.
Psychoneuroendocrinology
December 2024
Background: Appetite-regulating hormones are implicated in anorexia nervosa (AN) pathophysiology, however, data are limited for appetite-regulating hormones across the AN weight spectrum. We aimed to investigate fasting and post-prandial concentrations of appetite-regulating hormones - peptide YY (PYY), cholecystokinin (CCK), and ghrelin - among adolescent and young adult females across the AN weight spectrum, specifically those with AN and Atypical AN, and healthy controls (HC).
Methods: Participants (N = 95; ages 11-22 years) included 33 with AN, 25 with Atypical AN, and 37 HC.
Article Synopsis
- Tuberculosis (TB) is a major global health issue, particularly affecting the lungs, with an incidence rate of approximately 92 cases per 100,000 people; latent TB infection (LTBI) poses a significant concern due to its potential for transforming into active TB.
- A study in Malaysia analyzed 3,877 samples using the QuantiFERON®-TB Gold Plus test from January 2021 to March 2022, revealing a 16.46% prevalence of LTBI, particularly among males and individuals aged 30-43, predominantly of Chinese ethnicity.
- The findings highlight that age and ethnicity are significant risk factors for LTBI, and although the prevalence is low for a country with an intermediate TB burden,
Molecular modeling and cytotoxic activity studies of oxirane-2-carboxylate derivatives.
J Biomol Struct Dyn
November 2024
In this study, five 3-aryloxirane-2-carboxylate derivatives were prepared, and the antiproliferative activities of molecules were screened in lung and colon cancer cell lines. The results showed that molecules had antiproliferative activity on cancerous cells with IC values under 100 µM. Furthermore, all of the molecules were found to have a much higher cytotoxic effect than cisplatin in colon cancer cells.
View Article and Find Full Text PDFDeveloping novel hybrid bilayer nanofibers based on polylactic acid with impregnation of chamomile essential oil and gallic acid-stabilized silver nanoparticles.
Int J Biol Macromol
December 2024
This study presents fabrication and characterization of novel chamomile essential oil (CMO)/gallic acid-stabilized silver nanoparticles (gallic acid-nanosilver, GNS), embedded into polylactic acid (PLA)-based hybrid bilayer nanofibers (NFs). Where CMO was impregnated into polyvinyl alcohol (PVA)-polyethylene glycol (PEG) solution and electrospun simultaneously with PLA to obtain PLA/PVA-PEG-CMO NFs (PLA/CMO A2). Meanwhile, GNS were added to PVA-PEG-CMO and electrospun to obtain PLA/PVA-PEG-CMO-GNS NFs (PLA/CMO-GNS A3).
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