[Tuberculosis and opportunistic infections].

A serological study of blood from 44 patients with acutely progressive forms of pulmonary tuberculosis revealed their rather common association with active forms of the following opportunistic infections, such as M. pneumonia, Pn. carinii, and herpes simplex virus.

[Modeling and characteristics of liver damage in herpes infection].

An experimental model of herpetic hepatitis is developed, levels and time course of changes in transaminases, the main indicators of lipid metabolism, are characterized, and morphologic features of hepatocyte injury by herpes simplex virus are shown. Liver involvement in herpetic infection is described in detail.

[Role of lysosomes in immunodepression].

Degrading of heterologous protein--bovine serum albumin--under the action of lysosomes inhibited the immunodepressive preparations with chlorophos and 2,4-dichlorphenoxyacetic acid (2,4-D). Immunodepressors (chlorophos, 2,4-D, cyclophosphane, phosphestrol, methotrexate, ftuoruracil) suppressed the activity of cathepsin, whereas dibasol--an immunostimulant--failed to alter its activity. The principal possibility of the selective immunodepression at the level of lysosome enzymes is substantiated.