Experimental sharp force injuries to ribs: Multimodal morphological and geometric morphometric analyses using micro-CT, macro photography and SEM.

Tool marks on bones induced by knife blades can be analysed morphometrically in order to enable an allocation of the suspected "inflicting weapon" to the particular morphology of the bone lesions. Until now, geometric morphometrics has not been used to analyse the morphology of knife lesions on fleshed bones in detail. By using twelve experimental knives and a drop weight tower, stab/cut injuries were inflicted on untreated pig ribs.

Pathomorphologic findings in left ventricular hypertrabeculation/noncompaction of adults in relation to neuromuscular disorders.

Background: Aim of this study was to assess pathomorphologic findings (PATHO) in patients with echocardiographically (ECHO) diagnosed left ventricular hypertrabeculation/noncompaction.

Methods: ECHO-criteria for LVHT were: >3 trabeculations, moving synchronously with the compacted myocardium, and forming the noncompacted part of a two-layered myocardium. At autopsy, the hearts were investigated according to the pathologists' preferences.

Noncompaction in mitochondrial myopathy: visible on microscopy but absent on macroscopic inspection.

Objectives: Disappearance of left ventricular hypertrabeculation (LVHT) over time has been occasionally recognized, but absence on echocardiography and autopsy and presence on histological examination after autopsy has not been reported.

Methods: Routine investigations such as chocardiography, cardiac MRI and coronary angiography were applied. Autopsy studies included macroscopic inspection and dissection but also histological work-up.