Publications by authors named "M A Gonzalo Molina"

The scope of this article is to analyze the correlation between alcohol consumption and abdominal obesity in participants of the ELSA-Brasil cohort after a follow-up period of nine years. A longitudinal analysis was performed with baseline and follow-up data from ELSA-Brasil. At baseline, 15,105 civil servants were enrolled.

View Article and Find Full Text PDF

Objective: To assess the association between the combination of corporal adiposity (CA) and cardiorespiratory physical fitness (CRF) with cardiometabolic risk factors in children aged 7-10 years.

Methods: Cross-sectional observational study with a sample of 251 children registered in Family Health Units. Sociodemographic, lifestyle, anthropometric, biochemical, blood pressure, and CRF data were collected.

View Article and Find Full Text PDF

Background: Chronic obstructive pulmonary disease (COPD) and asthma are the two most prevalent chronic respiratory diseases, significantly impacting public health. Utilizing clinical questionnaires to identify and differentiate patients with COPD and asthma for further diagnostic procedures has emerged as an effective strategy to address this issue. We developed a new diagnostic tool, the COPD-Asthma Differentiation Questionnaire (CAD-Q), to differentiate between COPD and asthma in adults.

View Article and Find Full Text PDF
Article Synopsis
  • Major depressive disorder (MDD) is linked to neuroinflammatory processes involving the NLRP3 inflammasome, and a study examined the impact of the NLRP3 rs10754558 polymorphism on MDD diagnoses among young adults.
  • A population-based study with 1,100 participants found no significant association between the NLRP3 genotype and MDD diagnosis, but a clinical trial showed that individuals with the GG genotype had poorer treatment outcomes compared to those with GC/CC genotypes.
  • Longitudinal analyses indicated that GG individuals experienced less improvement in depressive and anxiety symptoms over time, suggesting that this genotype may affect the effectiveness of psychotherapy for MDD.
View Article and Find Full Text PDF