Publications by authors named "M A Firsov"
Article Synopsis
- The study aimed to assess the obstetric outcomes and urological complications related to asymptomatic bacteriuria (AB) in pregnant women using different diagnostic criteria.
- A total of 225 pregnant women participated, categorized into five groups based on their urine culture outcomes and treatment decisions, with factors like preterm birth and preeclampsia analyzed across these groups.
- Findings indicated that preterm birth was more common in all groups with AB, while preeclampsia was particularly prevalent in certain groups, though no significant differences were noted in complications such as hypertension or amnionitis.
The phototransduction cascade enables the photoreceptor to detect light over a wide range of intensities without saturation. The main second messenger of the cascade is cGMP and the primary regulatory mechanism is calcium feedback. However, some experimental data suggest that cAMP may also play a role in regulating the phototransduction cascade, but this would require changes in cAMP on a time scale of seconds.
View Article and Find Full Text PDFNon-tumorlesions of the kidneys in malignant neoplasms are very diverse. They can alter the results of chemotherapy and lead to death in the long term. In this regard, the related discipline of onconephrology has increasingly begun to be identified, which emphasizes the importance of diagnosing non-tumor kidney lesions in this category of patients.
View Article and Find Full Text PDFMany retinal degenerative diseases result in vision impairment or permanent blindness due to photoreceptor loss or dysfunction. It has been observed that Pde6b mice (rd1), which carry a spontaneous nonsense mutation in the gene, have a strong phenotypic similarity to patients suffering from autosomal recessive retinitis pigmentosa. In this study, we present a novel mouse model of retinitis pigmentosa generated through gene knockout using CRISPR/Cas9 technology.
View Article and Find Full Text PDFObjectives: The study presents a comparative analysis of the mini-percutaneous nephrolithotripsy (mini-PCNL) and retrograde nephrolithotripsy (RIRS) with a logistic analysis of outcomes and complications.
Material And Methods: The prospective study included 50 patients diagnosed with urolithiasis from 2018 to 2021 in the urological hospitals in Irkutsk. Patients were divided into two groups: RIRS (group I, n = 23) and Mini-PCNL (group II, n = 27).