Publications by authors named "M A F J van der Laar"
Background: For individuals who wish to reduce their cannabis use without formal help, there are a variety of self-help tools available. Although some are proven to be effective in reducing cannabis use, effect sizes are typically small. More insight into predictors of successful reduction of use among individuals who frequently use cannabis and desire to reduce/quit could help identify factors that contribute to successful cannabis use moderation.
View Article and Find Full Text PDFBackground: Recent studies have shown positive, though small, clinical effects of digital smoking cessation (SC) interventions for cancer survivors. However, research on associations among participant characteristics, intervention engagement, and outcomes is limited.
Objective: This study aimed to explore the predictors and moderators of engagement and outcome of MyCourse-Quit Smoking (in Dutch: "MijnKoers-Stoppen met Roken"), a digital minimally guided intervention for cancer survivors.
PERFECTRA: a pragmatic, multicentre, real-life study comparing treat-to-target strategies with baricitinib versus TNF inhibitors in patients with active rheumatoid arthritis after failure on csDMARDs.
RMD Open
May 2024
Article Synopsis
- The study compares the effectiveness of baricitinib and TNF-inhibitors (TNFi) in treating rheumatoid arthritis (RA) patients who did not respond to conventional treatments.
- A total of 199 patients were randomized, showing baricitinib to be both non-inferior and superior in achieving meaningful clinical responses at 12 weeks, with a higher percentage of patients reaching specified disease activity targets compared to TNFi.
- The results suggest that baricitinib may be a more effective initial treatment option than TNFi for RA patients who have failed previous therapies, based on the outcomes measured over 48 weeks.
Introduction: Polydrug use patterns among young adults using ecstasy vary, as well as their willingness to change them. Polydrug use patterns are likely associated with different adverse health outcomes. It is unknown whether polydrug use patterns of young adults who use ecstasy are similar in different countries.
View Article and Find Full Text PDFObjectives: Fatigue is prevalent in people with inflammatory rheumatic and musculoskeletal diseases (I-RMDs) and recognised as one of the most challenging symptoms to manage. The existence of multiple factors associated with driving and maintaining fatigue, and the evidence about what improves fatigue has led to a multifaceted approach to its management. However, there are no recommendations for fatigue management in people with I-RMDs.
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