Supracostal ultrasound guided approach percutaneous nephrolithotomy (SUGA-PNL) versus retrograde intrarenal surgery for large volume isolated upper calyceal stones: a prospective randomized analysis.

To assess outcomes of supracostal ultrasound guided approach percutaneous nephrolithotomy (SUGA-PNL) and retrograde intrarenal surgery (RIRS) in isolated large volume upper calyceal stones (UCS). This was a prospective randomized study including patients with isolated UCS > 20mm. The patients were randomized into two groups: group (P) (SUGA-PNL) and group (R) (RIRS).

Three-dimensional assessment of low-level laser therapy on orthodontic miniscrew displacement using CBCT: a retrospective study.

Background: This study aimed to assess the effect of Low-Level Laser Therapy (LLLT) on sagittal, transverse and vertical Orthodontic miniscrew displacement.

Materials And Methods: The study included CBCTs from the records of 12 adult patients who underwent upper first premolar extraction and canine retraction with orthodontic miniscrews for maximum anchorage. The miniscrews on one side received LLL, while the other side served as a control.

Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets.

Receptor-induced tyrosine phosphorylation of spleen tyrosine kinase (Syk) has been studied extensively in hematopoietic cells. Metabolic mapping and high-resolution mass spectrometry, however, indicate that one of the most frequently detected phosphorylation sites encompassed S297 (S291 in mice) located within the linker B region of Syk. It has been reported that Protein kinase C (PKC) phosphorylates Syk S297, thus influencing Syk activity.

Association between toxoplasmosis and autoimmune rheumatic diseases in Egyptian patients.

Purpose: To explore the association between T. gondii and autoimmune rheumatic diseases (ARDs).

Methods: This study involved 82 patients with ARDs: 44 rheumatoid arthritis (RA), 28 systemic lupus erythematosus (SLE), and 10 systemic sclerosis (SSc) and 61 age- and sex-matched controls.

IL-11 induces NLRP3 inflammasome activation in monocytes and inflammatory cell migration to the central nervous system.

The objective of this study is to examine IL-11-induced mechanisms of inflammatory cell migration to the central nervous system (CNS). We report that IL-11 is produced at highest frequency by myeloid cells among the peripheral blood mononuclear cell (PBMC) subsets. Patients with relapsing-remitting multiple sclerosis (RRMS) have an increased frequency of IL-11 monocytes, IL-11 and IL-11R CD4 lymphocytes, and IL-11R neutrophils in comparison to matched healthy controls.