Safety and Effectiveness of Highly Active Antiretroviral Therapy in Treatment-Naïve HIV Patients: Preliminary Findings of a Cohort Event Monitoring Study in Belarus.

Background And Objective: Antiretroviral drugs have well-documented evidence-based favorable benefit-risk ratios. Although various studies have investigated and characterized the safety profile of antiretroviral medicines, there are a limited number of studies evaluating the safety of first-line antiretroviral therapy (ART) in patients with a specific co-morbidity. A cohort event monitoring (CEM) study of the safety and effectiveness of antiretroviral medicines in a target population that has a significant level of co-morbidities (chronic infectious diseases, peripheral blood cytopenias) was implemented.

[The prevalence of chronic pathology of ENT organs and oral mucosa in the HIV-infected patients depending on their immune status].

The objective of the present study was to estimate the prevalence of chronic pathology of ENT organs and mucous membrane of the oral cavity in the HIV-infected patients depending on the number of cells containing CD4 markers in 1 mcl of blood plasma. It was shown that the prevalence of chronic pathology of ENT organs and oral mucosa in the HIV-infected patients depends on the number of cells carrying CD4 markers in 1 mcl of blood plasma. This pathology was found in 64.

Agreement in patient-physician communication in primary care: a study from Central and Eastern Europe.

Objective: Efficient patient-physician collaboration is proven to have a direct benefit on health care outcomes through improved compliance, appointment keeping and use of preventive services. The aim of this study was to evaluate the patient-physician agreement on communication during primary care consultations and consider possible discrepancies.

Methods: A cross-sectional survey using self-administered questionnaires was performed in primary care in four European countries (Lithuania, Slovenia, Serbia and Russia).

[Blood biochemical parameters of tilted primates periodically subjected to gravitational stimuli].

Head-down tilting of primates (HOT) is a universal method of studying the hypokinetic syndrome effects on functionality of various body systems. Clinical biochemical blood assay was performed in a 25-day HDT experiment (-5 degrees) with 11 Macaca rhesus. One group of animals was kept tilted all the time through, whereas the other was periodically returned into the orthostatic position for 30 to 120 minutes 4-5 times a week.

Physiological reactions of primates to 9-D immersion and head-down tilt.

Purpose of the investigation was to compare physiological reactions of primates (Macaca mulatta) to microgravity simulated by immersion and head-down tilt (HDT). In immersion experiments, primates in waterproof suits were put into motion-restraining chairs and immersed into water (t=35.4 degrees C) breast-deep for 9 days.