External Validation of Brief Resolved Unexplained Events Prediction Rules for Serious Underlying Diagnosis.

Importance: The American Academy of Pediatrics (AAP) higher-risk criteria for brief resolved unexplained events (BRUE) have a low positive predictive value (4.8%) and misclassify most infants as higher risk (>90%). New BRUE prediction rules from a US cohort of 3283 infants showed improved discrimination; however, these rules have not been validated in an external cohort.

Identifying serious underlying diagnoses among patients with brief resolved unexplained events (BRUEs): a Canadian cohort study.

Objective: To describe the demographics and clinical outcomes of infants with brief resolved unexplained events (BRUE).

Design: A retrospective cohort study.

Setting: 11 centres within the Canadian Paediatric Inpatient Research Network.

Avian injury quantification using the Shoreline Deposition Model and model sensitivities.

Deposition models, such as the Shoreline Deposition Model (SDM) used to quantify nearshore avian injuries resulting from the 2010 Deepwater Horizon (DWH) oil spill, were developed to improve the estimates of nearshore avian mortality resulting from the release of oil into coastal and marine environments. Unlike earlier approaches to injury quantification, such as simple counts of carcasses on the shoreline, a modeling approach allows trustees to evaluate the precision of their estimate (i.e.

A quantitative measure of handgrip myotonia in non-dystrophic myotonia.

Introduction: Non-dystrophic myotonia (NDM) is characterized by myotonia without muscle wasting. A standardized quantitative myotonia assessment (QMA) is important for clinical trials.

Methods: Myotonia was assessed in 91 individuals enrolled in a natural history study using a commercially available computerized handgrip myometer and automated software.

Use of continuous positive airway pressure (CPAP) in acute viral bronchiolitis: a systematic review.

Introduction: Continuous positive airway pressure (CPAP), used either alone or associated with heliox (CPAP-He), has become a popular therapeutic option for bronchiolitis. This systematic review assesses the impact of CPAP on endotracheal intubation, carbon dioxide pressure (PCO(2) ) and respiratory distress in patients with bronchiolitis.

Methods: Systematic search including studies that used CPAP or CPAP-He in infants with bronchiolitis admitted to a PICU.