Introduction: The increasing aging of the population brings with it an increase in the incidence of neurocognitive disorder (NCD) as well as various situations that generate dependence.
Objective: To analyze by means of a systematic review the relationship between NCD and dependence with the risk of mortality in the elderly.
Methods: A bibliographic search of longitudinal studies published in Pubmed and Scopus addressing the relationship between NCI, dependence for basic activities of daily living (ADL) and mortality published between 1995 and 2021 was performed.
Objective: To assess the safety and efficacy of port-locking with heparin every 2 months vs. every 4 months and vs. saline solution every 2 months in patients with cancer not receiving active chemotherapy.
View Article and Find Full Text PDFIn cutaneous T cell lymphoma (CTCL), a dominant Th2 profile associated with disease progression has been proposed. Moreover, although the production and regulation of IL-4 expression during the early stages of the disease may have important implications in later stages, these processes are poorly understood. Here, we demonstrate the presence of TOX CD4 T cells that produce IL-4 in early-stage skin lesions of CTCL patients and reveal a complex mechanism by which the NLRP3 receptor promotes a Th2 response by controlling IL-4 production.
View Article and Find Full Text PDFIntroduction: Mycosis fungoides (MF) is the most common primary skin T-cell lymphoma, which is characterized for a heterogeneous clinical expressivity.
Objective: To report clinical variants and sociodemographic characteristics in patients with MF under the care of a dermatological hospital.
Methods: 290 patients with MF clinical and histopathological diagnosis attended to over the course of 11 years were included.