Publications by authors named "M A Deangelis"
Article Synopsis
- Residents are required to engage in practice-based learning, typically through a patient follow-up log, but a new approach called the Patient Follow-Up Report (PFUR) was developed to enhance this process.
- The PFUR is an automated monthly email report generated from electronic medical records, categorizing patient cases for better tracking, including those readmitted, diagnosed, expired, or flagged for follow-up.
- After six months of using the PFUR, it significantly improved patient follow-up numbers, with 90% of residents preferring it over the previous method, as they found it valuable for both education and clinical care.
Article Synopsis
- Bulk deconvolution using single-cell RNA-seq is important for analyzing complex biological samples, but differences in sequencing technology can lead to inaccuracies.
- The researchers created a new framework called DeMixSC that improves deconvolution by utilizing well-matched benchmark datasets to account for these technological discrepancies.
- DeMixSC was tested on datasets from healthy retinas and ovarian cancer tissues, showing improved accuracy and the ability to reveal significant biological differences in patient groups, highlighting its usefulness in clinical applications.
Multiomic profiling of single cells by sequencing is a powerful technique for investigating cellular diversity. Existing droplet-based microfluidic methods produce many cell-free droplets, underutilizing bead barcodes and reagents. Combinatorial indexing on microplates is more efficient for barcoding but labor-intensive.
View Article and Find Full Text PDFRetinitis Pigmentosa is a leading cause of severe vision loss. Retinitis Pigmentosa can present with a broad range of phenotypes impacted by disease age of onset, severity, and progression. This variation is influenced both by different gene mutations as well as unique variants within the same gene.
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