[Can CPAP prevent the progression of pediatric acute respiratory distress syndrome? A decade of experience in a Reference Center].

Viral infections are the main cause of acute respiratory failure in infants, which can progress to acute respiratory distress syndrome (ARDS), with high morbidity and mortality, so it is essential to imple ment strategies that prevent this progression. Recently, it has been proposed that increased work of breathing would not only be a warning symptom during the evolution of acute respiratory failure, but also a mechanism for the progression of injury, both lungs and diaphragm, coining the concept of patient self-inflicted lung injury. Since the first reports of ARDS, the usefulness of the use of con tinuous positive airway pressure (CPAP) has been raised, a non-invasive respiratory support therapy with wide access and low cost, capable of improving oxygenation and work of breathing.

Multi-generational exposure of Daphnia magna to pharmaceuticals: Effects on colonization, reproduction, and habitat selection behavior.

The presence of pharmaceuticals in the aquatic environment is increasing due to their growing use for human health. Although most studies are based on short exposures to these contaminants, the present study has emerged from the need to study pharmaceuticals in aquatic organisms over a long-term exposure to understand any multi-generational chronic effects and alterations regarding habitat selection. Therefore, this study shows: (1) the ability of Daphnia magna to colonize environments contaminated with caffeine, ibuprofen and fluoxetine, and (2) the effect of these pharmaceuticals on reproduction and habitat selection (under two scenarios: with and without food) after a long-term exposure period of three generations.

Injuries of the Extensor Tendons of the Hand and Forearm.

Extensor tendon injuries are commonly encountered after trauma. These injuries often result in acute weakness and have widely differing treatment options depending on the severity and the location of the injury within the upper extremity. Zone I injuries can often be treated nonoperatively with the potential for pinning of any large bony avulsion fragments.