Publications by authors named "M A Ciccone"
Components of yeast cell walls, such as β-glucans and mannoproteins, show promise for developing sustainable biopolymers for food packaging. Efficient extraction, however, is challenging due to the complexity of the yeast cell wall. This study explored high-pressure homogenisation (HPH) and pulsed electric fields (PEFs), alone and with heat treatment (TT), on bakery yeast (BY) and brewery spent yeast (BSY) biomasses.
View Article and Find Full Text PDFArticle Synopsis
- A variety of conditions, both related to blood flow and not, can lead to ST-segment elevation (STE) on an ECG, one of which is the rare Takotsubo syndrome (TTS) often linked to low calcium levels.
- This paper discusses a unique case of a 75-year-old woman with advanced ovarian cancer, who showed signs on her ECG resembling a heart attack but was actually caused by severe hypocalcemia, with no prior heart issues.
- After ruling out coronary artery disease and providing calcium treatment, her heart function and ECG readings returned to normal, emphasizing the need to consider unusual causes of STE like hypocalcemia in patients with cancer.
Anderson-Fabry disease (AFD) remains a therapeutic challenge despite advances in early diagnosis and the availability of enzyme replacement therapies (ERTs). While early initiation of therapy can mitigate disease progression, resistance mechanisms-such as the development of anti-drug antibodies-limit the efficacy of current treatments, particularly in patients with severe genetic variants. Chaperone therapy provides a targeted option for a subset of patients, yet significant gaps remain in treating those with complete enzyme deficiency.
View Article and Find Full Text PDF