Publications by authors named "M A Chattaway"
Paratyphoid B fever (PTB) is caused by an invasive lineage (phylogroup 1, PG1) of Salmonella enterica serotype Paratyphi B (SPB). However, little was known about the global population structure, geographic distribution, and evolution of this pathogen. Here, we report a whole-genome analysis of 568 historical and contemporary SPB PG1 isolates, obtained globally, between 1898 and 2021.
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- Salmonella enterica serovar Agona (S. Agona) has emerged as a key cause of gastroenteritis, with unique adaptations such as biofilm formation and viable but non-culturable states aiding its persistence in humans.
- A study of 2233 S. Agona isolates from UK infections (2004-2020) examined the genome structure and phenotypes of different stages of infection to understand factors contributing to chronic carriage.
- Findings indicated that certain genome rearrangements and increased SNP variation are linked to early-stage and persistent infections, suggesting mechanisms for immune evasion and establishment of chronic infection.
Article Synopsis
- Wastewater surveillance helps track germs that can make people sick by checking the water we use, making it easier to spot problems in communities.
- This method shows how illnesses spread, even from people who don’t feel sick yet, which helps public health officials act quickly.
- While there are some challenges to improve, wastewater surveillance is super helpful in keeping us safe from diseases like COVID-19 and others.
Background: Gastrointestinal (GI) infections result in 17 million cases annually, with foodborne illness costing the National Health Service (NHS) £60m per year. The burden of GI infection is unequally distributed, with greater impact in more socioeconomically disadvantaged groups and areas. Local authorities (LA) provide vital services that protect public health and wellbeing.
View Article and Find Full Text PDFAim: To investigate the possible contamination of raw flour and raw flour-based products, such as pancake/batter mixes, with Salmonella, generic Escherichia coli, and Shiga-toxin-producing E. coli (STEC). Samples included flours available for sale in the UK over a period of four months (January to April 2020).
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