Case report: Novel variant of uncertain significance in a pediatric case of steroid-resistant nephrotic syndrome requesting kidney transplantation.

Background: Steroid-resistant nephrotic syndrome (SRNS) is a rare kidney disease commonly characterized histopathologically by focal and segmental glomerulosclerosis (FSGS) or minimal change disease. One-third of SRNS-FSGS cases are attributed to a genetic cause ultimately leading to end-stage kidney disease (ESKD) during childhood or adulthood. variants, although rare, typically manifest in early adulthood as SRNS-FSGS with autosomal dominant inheritance pattern and are associated with variable progression toward ESKD.

e-Health applications for outpatient professional pharmaceutical care services: A scoping review.

Background: eHealth, or electronic or digital health, integrates information and communication technologies (ICT) into healthcare, including professional pharmaceutical care services. Nevertheless, to date, there is a lack of guidance in establishing the technologies' requirements, design, and implementation. Therefore, it urges the need to conduct a study regarding this topic is needed.

The Wildcat That Lives in Me: A Review on Free-Roaming Cats () in Brazil, Focusing on Research Priorities, Management, and Their Impacts on Cat Welfare.

Domestic cats () currently occupy the 38th place in the Global Invasive Species Database. Free-roaming cats potentially have broad-ranging impacts on wildlife, occupying most terrestrial environments globally as house pets, strays, or feral animals. In Australia, for example, cats are responsible for the decline in many vertebrate populations and extinction of several native mammals.

A New Graphical Method for Displaying Two-Dimensional Echocardiography Results in Dogs: Comprehensive Analysis of Results of Diagnostic Imaging Organized in a BOX (CARDIOBOX).

Introduction And Objective: Rapid and efficient interpretation of echocardiographic findings is critical in clinical decision-making. This study aimed to design and validate a new graphical method, called CARDIOBOX, to represent echocardiographic findings in dogs.

Methods: A prospective, observational, exploratory cohort study was conducted over three years.

Ultrafast synthesis of zirconium-porphyrin framework nanocrystals from alkoxide precursors.

Porphyrinic metal-organic frameworks (MOFs) offer high surface areas and tunable catalytic and optoelectronic properties, making them versatile candidates for applications in phototherapy, drug delivery, photocatalysis, electronics, and energy storage. However, a key challenge for industrial integration is the rapid, cost-effective production of suitable sizes. This study introduces Zr(IV) alkoxides as metal precursors, achieving ultrafast (∼minutes) and high-yield (>90%) synthesis of three well-known Zr-based porphyrinic MOF nanocrystals: MOF-525, PCN-224, and PCN-222, each with distinct topologies.