Publications by authors named "M A Bullimore"
Purpose: To explore evidence for myopic shift between the ages of 20 and 50 years.
Methods: Three usable sets of data with long-term adult refractive progression were identified: (1) US population-based prevalence data for those 18 to 24 years of age in 1971 and 1972 and 45 to 54 years of age from 1999 to 2004; a logit transformation of prevalence values at different refractive error thresholds allowed estimation of myopic progression in this group. (2) German clinical data describing 5- to 10-year progression for different refractive error groupings across 5-year age bands from 20 to 49 years; these were extracted, adjusted, and analyzed.
Purpose: When myopia control treatment is discontinued, progression will increase, but does it revert to expected values based on the age and race of the child or does it accelerate further? The latter scenario is considered a rebound.
Methods: A PubMed search was conducted with the words 'rebound' and 'myopia control', identifying further papers from reviews. Inclusion was limited to prospective studies with ≥6 months of treatment, ≥3 months of data following cessation and with axial length data, which allowed calculation of rebound.
Is the Change in Prevalence of High Myopia Compared to That of Myopia Really Disproportionate?
Transl Vis Sci Technol
October 2024
Article Synopsis
- The study explores the relationship between the prevalence of high myopia and myopia, noting that as overall myopia rates increase, high myopia rates rise at a faster rate.
- It uses data from 41 datasets to model how changes in myopia prevalence impact the prevalence of high myopia, demonstrating that the ratio of increase varies with overall myopia rates.
- The findings suggest that while interventions may effectively influence high myopia prevalence, strategies aimed at delaying the onset of myopia will be more impactful for both conditions.
Article Synopsis
- The study focuses on understanding how axial elongation, a key factor in the progression of primary myopia in children, is affected by various factors through a meta-regression analysis.
- Researchers conducted a systematic search of multiple databases, analyzing data from 64 studies to model the mean rate of axial elongation in low to moderate myopia cases.
- Results revealed that axial elongation is significantly greater in Asian children compared to non-Asians, with both groups showing a consistent decline in elongation rates as they age, highlighting the complexity of managing myopia in individual children.
Can we really distinguish 'responders' from 'non-responders' to myopia control interventions?
Ophthalmic Physiol Opt
November 2024
Purpose: It is common to hear talk of 'responders' and 'non-responders' with respect to myopia control interventions. We consider the reality of distinguishing these sub-groups using data from the first year of the Low-concentration Atropine for Myopia Progression (LAMP) study.
Methods: The first year of the LAMP study was a robustly designed, placebo-controlled trial of three different low concentrations of atropine using a large sample size (N > 100 randomised to each group).