[Is there an association of uric acid level with preclinical target organ damage in moderate- and high-risk hypertensive patients?].

Aim: To assess an association of uric acid level with preclinical target organ damage in patients with hypertensive disease (HD).

Subjects And Methods: The trial enrolled 100 patients (63 men and 37 women) with Stage I-II HD at moderate and high risk for cardiovascular events (CVEs). The mean age of the patients was 44.

[Obstructive sleep apnea and a cardiovascular risk in patients with arterial hypertension].

Objective: To study an independent role of the obstructive sleep apnea syndrome (OSAS) in patients with arterial hypertension (AH) according to the data of a retrospective observation.

Subjects And Methods: all patients underwent polysomnographic test (EMBLA Flaga, Iceland) and the frequency of unfavorable events (stroke, myocardial infarction, chronic heart failure, atrial fibrillation, intermittent claudication, or death) was determined during the case-control observational longitudinal retrospective study. The diagnosis of OSAS was made when the apnea-hypopnea index (AHI) of more than 15 events per hour of sleep; the patients with an AHI of less than 15 formed a control group.

[New methods of evaluation of the human-operator reliability].

New methods to evaluate the human operator reliability were tested with participation of 27 students of the Air Traffic Control Faculty at the Civil Aviation Academy. One of the proposed criteria is reactivity of the sympathetic cardiovascular regulation as determined during a cold hypoxic-hypercapnic exposure. By this criterion, the subjects divided into a reactive and a super-reactive group.

[Pharmacological correction of myocardial ischemia and arrhythmias in reversible coronary blood flow disorders and experimental myocardial infarct in dogs].

The efficacy of the sum of alkaloids of the common fumitory in temporary disorders of the coronary blood flow in the circumflex artery was studied in chronic experiments on 8 dogs. Occlusion of the vessel was caused by means of a remote-controlled loop implanted into the thoracic wall. The arrest of circulation in the artery was attended by the appearance of pathological signs on the ECG in the form of tachycardia, growth of the T wave amplitude, and displacement of the RS-T interval.

[Changes in organelle-specific enzyme activity and the ultrastructure of liver cells in cholelithiasis].

Activities of organelle specific enzymes (succinate dehydrogenase, glucose-6-phosphatase, acidic DNAase, acidic RNAase, acidic and alkaline phosphatases) were measured in homogenates and subcellular fractions of liver tissue of patients with cholelithic disease. Liver tissue samples analyzed were investigated also by light and electron microscopy. The data obtained were considered in connection with localization of cholelith in biliary system, type of inflammation, presence of subhepatic cholestasis and of accompanying syndrome of pancreatitis.