Publications by authors named "M A Bodi"
Reformulating real-time random safety analysis during the SARS-CoV-2 pandemic.
Med Intensiva (Engl Ed)
December 2024
Introduction: From a safety perspective, the pandemic imposed atypical work dynamics that led to noticeable gaps in clinical safety across all levels of health care.
Objectives: To verify that Real-Time Random Safety Analyses (AASTRE) are feasible and useful in a high-pressure care setting.
Design: Prospective study (January-September 2022).
: Bacterial/fungal coinfections (COIs) are associated with antibiotic overuse, poor outcomes such as prolonged ICU stay, and increased mortality. Our aim was to develop machine learning-based predictive models to identify respiratory bacterial or fungal coinfections upon ICU admission. : We conducted a secondary analysis of two prospective multicenter cohort studies with confirmed influenza A (H1N1)pdm09 and COVID-19.
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- Over the last decade, research has focused on how mechanical power contributes to ventilation-induced lung injury and its potential link to ICU mortality, but most studies have only looked at early mechanical ventilation data.
- This study analyzed mechanical power in patients ventilated for over 24 hours in a Spanish ICU, determining how prolonged exposure to high mechanical power impacts mortality rates and hospital stay duration.
- Researchers established that a mechanical power threshold of 18 J/min significantly correlates with increased ICU mortality; specifically, the risk of death rises by 0.1% for each additional hour patients are ventilated above this threshold.
Patient safety is a priority for all healthcare systems. Despite this, too many patients still suffer harm as a consequence of healthcare. Furthermore, it has a significant impact on family members, professionals and healthcare institutions, resulting in considerable economic costs.
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- Liposomal amphotericin B (L-AmB) is a key treatment for severe fungal infections, but it may pose risks for kidney damage in critically ill patients.
- A study analyzed 67 patients treated with L-AmB for over 48 hours to determine the incidence of acute kidney injury (AKI), revealing that 26.8% of patients developed AKI, with lower rates in those at higher initial risk.
- Key factors contributing to AKI included norepinephrine use, SOFA scores, and certain laboratory results, indicating that while L-AmB appears safe, AKI development is influenced by multiple factors.