Publications by authors named "M A Belmonte"

Background: Coronary computed tomography angiography (CCTA) is emerging as a valuable tool for noninvasive surveillance of cardiac allograft vasculopathy (CAV) in patients with heart transplant (HTx). We assessed the diagnostic performance of a comprehensive CCTA-based approach compared with the invasive reference, which includes invasive coronary angiography, intravascular ultrasound, and fractional flow reserve, for detecting CAV.

Methods: This was a multicenter prospective study including 37 patients with HTx who underwent CCTA, invasive coronary angiography, intravascular ultrasound, and fractional flow reserve.

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Article Synopsis
  • The study investigates myocardial infarction with non-obstructive coronary arteries (MINOCA), revealing that its underlying causes are diverse and not well understood in clinical settings.
  • A review of 45 studies found that 53% of patients with MINOCA had non-obstructive coronary artery stenosis, with significant findings from optical coherence tomography and vasomotor tests.
  • Patients with non-obstructive coronary arteries showed a higher risk of death or myocardial infarction at one year compared to those with normal arteries, indicating the need for better diagnostic methods in understanding MINOCA.
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Background The detection of in-stent restenosis (ISR) with coronary CT angiography (CCTA) is challenging, but CT perfusion (CTP) has demonstrated improved diagnostic accuracy over CCTA in patients with stents. However, there are limited data on the performance of dynamic CTP, which allows noninvasive adjudication of regional myocardial blood flow. Purpose To compare the diagnostic performance of regadenoson-stress dynamic CTP with that of CCTA, using fractional flow reserve (FFR) and the index of microvascular resistance (IMR) as reference standards for epicardial coronary circulation and coronary microcirculation, respectively.

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Article Synopsis
  • Robotic-assisted coronary interventions (R-PCI) have shown safety and effectiveness in treating various coronary lesions, but their real-world clinical outcomes remain unclear.
  • A study evaluated 111 patients to assess major adverse cardiovascular events (MACE) and found a low occurrence of 5.4% during a median follow-up period.
  • The research indicated that while procedural complexity increased time and radiation exposure, it did not impact in-hospital or long-term outcomes, and CCTA-guided procedures allowed for a higher rate of same-day discharge (64.6% vs. 44.2%).
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