Publications by authors named "M A Basterrechea Sanz"

Aim: To evaluate in vitro the antibacterial efficacy and cytocompatibility of different implant-decontamination methods, using both 2D and 3D peri-implant mucosa models.

Methods: Four decontamination methods [chlorhexidine (CHX), electrolytic treatment (GS), curcumin (CUR), xanthohumol (XN)] were compared in four independent experiments, three with a 2D peri-implant mucosa model on titanium surfaces and another on a 3D peri-implant mucosa model. These decontamination procedures were tested for their antibacterial effect using a multispecies biofilm model with Streptococcus oralis, Actinomyces naeslundii, Veillonella dispar, and Porphyromonas gingivalis for 24 h.

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Introduction: Cholemic nephropathy is an overlooked cause of acute kidney injury (AKI) in patients with advanced cirrhosis and high bilirubin plasma levels (usually above 20mg/dl), due to bilirubin and bile acid deposition in the kidneys. Those deposits have been hypothesized to cause tubular injury. It has no standardized diagnostic criteria or therapeutic strategies.

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Aim: This prospective cohort study aimed to evaluate the incidence and risk/protective factors of peri-implantitis over time.

Methods: A university-representative cohort was evaluated at baseline and after a mean follow-up time of 3.9 years.

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BK hemorrhagic cystitis (BK-HC) is a common complication following hematopoietic stem cell transplantation (HSCT), particularly when posttransplant cyclophosphamide (PTCy) is used as graft-versus-host disease (GVHD) prophylaxis. However, comparative studies of BK-HC incidence in matched sibling donors (MSD) and unrelated donors (MUD) often include small haploidentical (HAPLO) donor cohorts and usually lack detailed information on disease evolution, coinfections, management and impact on outcomes. This study aimed to evaluate the incidence, risk factors, and outcomes in patients with hematologic malignancies undergoing HSCT from MSD, MUD, HAPLO donors using PTCy as GVHD prophylaxis.

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Article Synopsis
  • Coleus forskohlii supplements (FKSs), popular for weight management due to forskolin, face issues like fraud and adulteration.
  • A new method using Flow Injection Analysis-Mass Spectrometry (FIA-MS) was developed to effectively detect these issues in FKSs.
  • The method revealed that 45% of tested samples did not contain forskolin, and there was a 69% discrepancy between the actual and labeled forskolin content, demonstrating FIA-MS as a reliable technique for quality assessment.
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