Publications by authors named "M A Bal"
The cholangioblastic variant of intrahepatic cholangiocarcinoma is a distinctive neoplasm that typically affects young women without underlying liver disease. Morphologically, it demonstrates solid, trabecular, and tubulocystic architecture, biphasic small cell-large cell cytology, and immunoreactivity for inhibin, neuroendocrine markers, and biliary but not hepatocellular markers. In 2021, our group identified a characteristic NIPBL::NACC1 gene fusion in cholangioblastic cholangiocarcinoma, and since then ~20 genetically confirmed cases have been reported in the literature.
View Article and Find Full Text PDFThis systematic review study examines the relationship between language development, executive function, and screen time in early childhood. The early childhood period is a crucial phase for the development of the brain, during which fundamental language and executive function skills undergo rapid evolution. This review synthesizes findings from 14 peer-reviewed studies that focused on language development, executive function, and screen time together to provide a comprehensive understanding of their relationship.
View Article and Find Full Text PDFNull mutations for genes encoding a major seed storage protein in pea, vicilin, were sought through screening a fast-neutron mutant population. Deletion mutations at four or five vicilin loci, where all vicilin genes within each locus were deleted, were combined to address the question of how removal or reduction of a major storage protein and potential allergen might impact the final concentration of protein per unit mature seed weight, seed yield and viability. While the concentration of seed protein was not reduced in mature seeds of mutant lines, indicative of a re-balancing of the proteome, notable differences were apparent in the metabolite, proteomic and amino acid profiles of the seeds, as well as in some functional properties.
View Article and Find Full Text PDFArticle Synopsis
- A growing interest in applying complex systems methods to study socioeconomic inequalities in health is found, but there's a noticeable gap in how these methods are actually utilized in research.
- The analysis reveals that studies employing more complex systems concepts also provide better reporting on relationships within the data, but the underlying beliefs within the system are often overlooked.
- The authors emphasize the need for better reporting practices, including a full depiction of model structures, and suggest creating guidelines to enhance clarity and effectiveness in future studies.
Article Synopsis
- Fine needle aspiration (FNA) is a key method for diagnosing salivary gland lesions, and the modified MSRSGC helps standardize FNA report classifications.
- In a study of 325 patients treated from 2012 to 2019, the sensitivity of the modified MSRSGC was 64.18%, and its specificity was 91.94%.
- The use of frozen sections (FS) primarily aimed to establish a primary diagnosis, mostly showing malignancy when FNA results were classified as type V or higher, indicating that FS may not significantly enhance intraoperative decision-making.