A prospective multicenter cohort study of frailty in younger critically ill patients.

Background: Frailty is a multidimensional syndrome characterized by loss of physiologic and cognitive reserve that heightens vulnerability. Frailty has been well described among elderly patients (i.e.

Blood pressure, vascular resistance, and +Gz tolerance during repeated +Gz exposures.

Background: Cardiovascular reflexes that regulate blood pressure (BP) adapt during repeated exposure to +Gz acceleration separated by short (< 20 s) breaks, but whether this effect is preserved with longer intervals remains unknown.

Methods: There were 17 subjects who completed 5 repeated gradual onset (0.1 G x s(-1)) runs (GOR1-5) to 60 degrees peripheral light loss (PLL) on a human centrifuge, separated by 2 min.

Anaesthesia and the autistic child.

There appears to be little literature in paediatric anaesthetic practice relevant to children suffering with autism (Rainey & Van der Walt 1998). Recent findings suggest a need for rigorous study of the potential problems that autistic children may have when undergoing an anaesthetic (Kirz 2007). Some healthcare professionals do not have the knowledge or professional guidance to be able to identify these children (DH 2001, Disability Rights Commission 2006, DH 2008a, b, 2009, Rankin 2009).

The role of 18F-FDG PET/CT imaging in Waldenstrom macroglobulinemia.

Disease assessment in WM is dependent on the quantification of the IgM monoclonal protein and percent involvement of the bone marrow. There is a need for imaging studies that objectively measure tumor load in these patients. In this study, we sought to examine the role of combined FDG-PET/CT imaging in the detection of tumor load and in the assessment of response to therapy.