Publications by authors named "M A Ayadi"
Background: Central nervous system (CNS) tumors are the leading cause of cancer-related deaths in children. While most cases come from low-middle income countries (LMIC) where their prognosis is worse, few epidemiological studies are conducted in these regions.
Methods: We conducted a registry-based cohort study for childhood CNS tumors at Children's Cancer Hospital, Egypt (CCHE) over 15 years.
Article Synopsis
- HLA-G 14-bp insertion/deletion polymorphism is linked to cancer risk, particularly associated with the D allele, suggesting it may contribute to cancer cell escape mechanisms.
- A meta-analysis of 39 studies showed a significant association between this polymorphism and breast cancer, with specific variations in risk based on ethnicity and geographic location.
- Significant cancer risks linked to the D allele were observed in populations from North Africa, the Middle East, and South America, but no such risks were noted in Europe or North Asia.
Olive mill wastewater (OMWW) was used in ferti-irrigation due to its high water content, as well as its organic and mineral richness. However, this by-product also contains elevated levels of polyphenols, which may pose phytotoxic risks to soil microbiota and plants over time. To address this concern, we conducted a thorough examination of the phenolic composition of OMWW and the phenolic content of amended soils using HPLC analysis.
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- Innovations in advanced prostate cancer have improved outcomes, but there's still a lack of high-level evidence in clinical management, prompting the 2024 Advanced Prostate Cancer Consensus Conference to survey experts for insights.
- A panel of 120 international experts developed and voted on 183 consensus questions through a web-based survey prior to the conference, defining consensus as ≥75% agreement.
- The voting results highlight areas of agreement and disagreement that can guide clinical decisions and future research, with a focus on individualizing treatment based on patient characteristics and encouraging participation in clinical trials.