[Circadian rhythms of mineral-excreting kidney function in healthy persons and their changes in ischemic heart disease].

Seventy normal persons and 100 patients with coronary disease were examined for circadian rhythms of urine and minerals excretion. The data obtained demonstrate that normal persons were characterized by circadian rhythms of urine and minerals excretion with a definite confidence interval of mesor and amplitude fluctuations. Angina pectoris of effort was marked by infradian rhythms of mineral excreting renal function.

[Effect of anti-anginal therapy on the functional state of the myocardium in patients with chronic ischemic heart disease].

Antianginal therapy with long-acting nitrates, beta-blockers, and combinations there of were administered depending on the baseline cardiovascular function, as assessed by spiroergometry, in 300 patients with chronic coronary heart disease. Three degrees of the hypokinetic type corresponding to the degrees of myocardial failure were identified on the basis of adaptability patterns and the disturbance of correlations between the increment in oxygen consumption, heart rate, cardiac output, and the output of work done. It is shown that cardiovascular status should be taken into account in selecting the type of antianginal therapy for chronic coronary patients.