Publications by authors named "M A Archana"

Extracellular vesicles (EVs) have emerged as promising biomarkers in liquid biopsy, owing to their ubiquitous presence in bodily fluids and their ability to carry disease-related cargo. Recognizing their significance in disease diagnosis and treatment, substantial efforts have been dedicated to developing efficient methods for EV isolation, detection, and analysis. EVs, heterogeneous membrane-encapsulated vesicles secreted by all cells, contain bioactive substances capable of modulating recipient cell biology upon internalization, including proteins, lipids, DNA, and various RNAs.

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  • Researchers wanted to see how the structure of bone in the jaw differs when there are teeth (dentulous) and when there aren't (edentulous).
  • They studied 90 scans of people's jaws to measure this bone structure using special computer tools.
  • The results showed that the bone structure is different in areas with and without teeth, which can help doctors understand how to treat patients who need dental implants.
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  • - The study investigates how accurately foramen magnum dimensions can determine sex among South Indians using discriminant functional analysis based on CBCT images from 200 participants.
  • - It finds that males have significantly larger foramen magnum measurements compared to females, with a 73.5% accuracy rate in determining sex through these dimensions alone.
  • - The overall effectiveness drops to 66.5% when combining various measurements, suggesting that this method is best suited for cases with partial skulls rather than complete ones.
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Introduction: Telomere length related studies are limited in pediatric marrow failure cases due to difficulty in establishing population specific age related normograms. Moreover, there is paucity of data related to clinical relevance of telomere length in idiopathic aplastic anemia (IAA) and non telomere biology inherited bone marrow failure syndrome (IBMFS) cases.

Methodology: Hence, in current study we investigated Relative telomere length (RTL) by RQ-PCR in 83 samples as: healthy controls (n = 44), IAA (n = 15) and IBMFS (n = 24).

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