Publications by authors named "M A Arata"

Natural products have a long history of providing probes into protein biosynthesis, with many of these compounds serving as therapeutics. The marine natural product girolline has been described as an inhibitor of protein synthesis. Its precise mechanism of action, however, has remained unknown.

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Objective: WHO recommends the use of the Robson's 'Ten Groups Classification' for monitoring and assessing caesarean section (CS) rates. The aim of this study was to investigate the rates, indications and outcomes of CS using Robson classification in a tertiary hospital in Sierra Leone.

Design: Cross-sectional study.

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Article Synopsis
  • Previous studies indicate that androgen effects on body weight and appetite vary based on estrogen levels in females, but the exact mechanisms remain unknown.
  • The research tested the hypothesis that androgens influence oxytocin levels, an anorectic factor, in ovariectomized female rats with and without estradiol supplementation.
  • Findings revealed that testosterone increased oxytocin levels and reduced appetite in estrogen-deficient rats, while having no effect in those with estradiol, suggesting a link between androgens, oxytocin, and appetite regulation influenced by estrogen levels.
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Polycystic ovary syndrome (PCOS) is associated with an increased risk of psychological distress as well as enhanced responses to psychosocial stress. Recently, it was hypothesized that PCOS patients may be at high risk of novel COVID-19 infections and worse clinical presentations during such infections. Here, we evaluated the effects of PCOS on stress responses to bacterial and viral mimetics using dihydrotestosterone-induced PCOS model rats.

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