Publications by authors named "M A Apicella"
We characterized daily dietary protein intakes, focusing on protein source (animal and nonanimal) and form (whole-foods and supplemental) in young (18-40 years) resistance trained (training ≥ 3×/week for ≥ 6 months; TRA; male, n = 30; female, n = 14) and recreationally active (no structured training; REC; male, n = 30; female, n = 30) individuals. Using 3-day weighed food diaries from 10 previous studies, we assessed macronutrient intakes using dietary analysis software. Energy intakes trended greater in TRA compared with REC (p = .
View Article and Find Full Text PDFAim: To assess the efficacy and safety of autologous cell therapy (ACT) in patients with ischemic diabetic foot ulcers (DFU). The present meta-analysis was designed to support the development of the Italian Guidelines for the Treatment of Diabetic Foot Syndrome (DFS).
Methods: A Medline and Embase search were performed up to Feb 1st, 2024 collecting all RCTs including diabetic patients or reporting subgroup analyses on diabetic patients with ischemic foot ulcers comparing ACT with placebo/no therapy/standard of care (SoC), with a duration of at least 26 weeks.
Article Synopsis
- Contact-dependent hemolysins are key virulence factors in certain human pathogens, like gonococci, with phospholipase A being a notable outer membrane protein that can lyse human red blood cells over three days.
- Mutations in the phospholipase A gene significantly impair the bacteria's ability to survive in human immune cells, indicating its critical role in pathogenesis.
- The inability of phospholipase A mutants to effectively lyse host cells underscores its importance for gonococcal survival and evasion of the host's immune response.
Importance: There are suggestions that school pressure may be stressful and a factor in child and adolescent mental health disturbances, but data about this association are scarce and inconclusive.
Objective: To assess whether varying degrees of school interruption were associated with changes in emergency department (ED) psychiatric visits of children and adolescents before and after the COVID-19 outbreak.
Design, Setting, And Participants: A cross-sectional observational study was conducted at 9 urban university hospitals in Italy.